Tom Eirik Mollnes Selected Research

lepirudin (Refludan)

1/2022	Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood.
12/2021	Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood.
9/2002	Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation.

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Tom Eirik Mollnes Research Topics

Disease

48	Inflammation (Inflammations) 10/2022 - 09/2002
22	Sepsis (Septicemia) 03/2022 - 01/2008
12	Infections 01/2021 - 03/2003
8	Atherosclerosis 01/2022 - 01/2009
7	Reperfusion Injury 01/2022 - 01/2008
6	Thrombosis (Thrombus) 01/2021 - 10/2008
5	Neoplasms (Cancer) 10/2022 - 01/2008
5	Wounds and Injuries (Trauma) 11/2021 - 12/2019
5	Disease Progression 08/2021 - 04/2003
5	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 07/2012 - 01/2009
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2008
4	Septic Shock (Toxic Shock Syndrome) 01/2020 - 12/2004
4	Hereditary Complement Deficiency Diseases 01/2017 - 09/2007
4	Ischemia 03/2013 - 10/2008
4	Meningococcal Infections 11/2009 - 01/2002
3	Neoplasm Metastasis (Metastasis) 10/2022 - 09/2018
3	Rheumatoid Arthritis 01/2022 - 12/2013
3	Shock 01/2022 - 11/2011
3	Thromboinflammation 12/2021 - 01/2019
3	Necrosis 07/2020 - 06/2019
3	Atypical Hemolytic Uremic Syndrome 01/2018 - 04/2015
3	Fatigue 12/2017 - 05/2013
3	Chronic Kidney Failure (Chronic Renal Failure) 01/2017 - 07/2010
3	HIV Infections (HIV Infection) 08/2015 - 04/2003
3	Meconium Aspiration Syndrome 01/2015 - 10/2008
3	Hypoxia (Hypoxemia) 02/2010 - 10/2006
2	Heart Arrest (Cardiac Arrest) 01/2022 - 01/2021
2	Mental Disorders (Mental Disorder) 01/2022 - 01/2018
2	COVID-19 01/2022 - 12/2020
2	Ischemic Stroke 12/2021 - 08/2021
2	Stroke (Strokes) 12/2021 - 01/2007
2	Venous Thromboembolism 11/2021 - 01/2018
2	Heart Failure 01/2021 - 01/2017
2	Multiple Trauma (Multiple Injuries) 01/2021 - 01/2021
2	Hemolysis 10/2020 - 01/2019
2	Atherosclerotic Plaque (Atheroma) 10/2020 - 01/2016
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2020 - 10/2018
2	Hypersensitivity (Allergy) 01/2019 - 01/2016
2	Mannose-Binding Protein Deficiency 01/2018 - 02/2010
2	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 12/2017 - 05/2015
2	Acquired Immunodeficiency Syndrome (AIDS) 08/2015 - 01/2007
2	Hypothermia 09/2010 - 03/2009

Drug/Important Bio-Agent (IBA)

50	Complement System Proteins (Complement)IBA 03/2022 - 09/2002
29	CytokinesIBA 01/2022 - 03/2003
17	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
8	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2021 - 12/2004
7	Interleukin-6 (Interleukin 6)IBA 12/2020 - 03/2003
6	Interleukin-8 (Interleukin 8)IBA 01/2022 - 03/2003
6	Complement C5 (Complement 5)IBA 01/2021 - 07/2011
6	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021 - 08/2008
6	Glucose (Dextrose)FDA LinkGeneric 12/2019 - 10/2006
6	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2018 - 04/2003
6	oxidized low density lipoproteinIBA 11/2016 - 01/2009
5	C-Reactive ProteinIBA 01/2022 - 05/2009
4	Thrombin FDA Link 01/2022 - 07/2011
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 03/2003
4	CholesterolIBA 01/2017 - 07/2011
4	Proteins (Proteins, Gene)FDA Link 01/2016 - 07/2007
4	ChemokinesIBA 01/2016 - 03/2003
4	Immunoglobulin G (IgG)IBA 01/2016 - 05/2013
3	lepirudin (Refludan)FDA Link 01/2022 - 09/2002
3	Oxygen (Dioxygen)IBA 01/2021 - 03/2009
3	LDL Lipoproteins (beta Lipoproteins)IBA 10/2020 - 01/2011
3	eculizumab FDA Link 03/2017 - 04/2015
3	Complement Inactivating AgentsIBA 01/2017 - 02/2009
3	Interleukin-10 (Interleukin 10)IBA 01/2016 - 03/2003
3	Lactic Acid (Lactate)FDA LinkGeneric 03/2013 - 10/2008
3	Pyruvic Acid (Pyruvate)IBA 03/2013 - 10/2008
2	RNA (Ribonucleic Acid)IBA 03/2022 - 01/2021
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022 - 08/2015
2	Peptides (Polypeptides)IBA 01/2022 - 08/2017
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022 - 12/2017
2	NeopterinIBA 12/2021 - 11/2018
2	Pharmaceutical PreparationsIBA 11/2021 - 09/2010
2	LDL CholesterolIBA 10/2020 - 07/2012
2	LipopolysaccharidesIBA 01/2020 - 01/2008
2	EndotoxinsIBA 01/2020 - 01/2002
2	salicylhydroxamic acid (SHAM)IBA 01/2020 - 12/2019
2	pro-brain natriuretic peptide (1-76)IBA 10/2019 - 01/2017
2	Troponin T (Troponin T1)IBA 10/2019 - 11/2009
2	Immunoglobulin M (IgM)IBA 01/2019 - 05/2013
2	AntigensIBA 01/2019 - 01/2014
2	AnaphylatoxinsIBA 08/2017 - 07/2010
2	Complement Factor D (Factor D)IBA 01/2017 - 06/2006
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2016 - 09/2009
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2016 - 07/2010
2	InterferonsIBA 01/2016 - 01/2016
2	LectinsIBA 01/2016 - 11/2009
2	AntibodiesIBA 11/2013 - 10/2006
2	Interleukin-1beta (Interleukin 1 beta)IBA 05/2010 - 03/2003

Therapy/Procedure

11	Therapeutics 01/2022 - 07/2011
7	Blood Component Removal (Apheresis) 11/2016 - 01/2009
4	Liver Transplantation 03/2013 - 10/2008
4	Catheters 03/2013 - 01/2007
3	Transplantation 01/2022 - 12/2008
3	Renal Dialysis (Hemodialysis) 01/2011 - 01/2007
2	Radiotherapy 10/2022 - 09/2018
2	Kidney Transplantation 01/2022 - 12/2008
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2019 - 01/2017
2	Plasmapheresis 09/2010 - 01/2007